北京时间10月11日，2018英雄联盟全球总决赛正赛小组赛第二日首发名单公布，19时iG对阵GRX上单Duke首发，21时RNG与GEN老冤家压轴对决，依旧派出狼王Karsa登场。
首发名单
FW - Hanabi, Moojin, Maple, Betty, SwordArt
PVB - Zeros, Meliodas, Naul, BigKoro, Palette
AFS - Kiin, Spirit, Kuro, Kramer, TusiN
G2 - Wunder, Jankos, Perkz, Hjarnan, Wadid
RNG - Letme, Karsa, Xiaohu, Uzi, Ming
GEN - Cuvee, Haru, Crown, Ruler, CoreJJ
VIT - Cabochard, Kikis, Jiizuke, Attila, Jactroll
C9 - Licorice, Svenskeren, Jensen, Sneaky, Zeyzal
FNC - Soaz, Broxah, Caps, Rekkles, Hylissang
100 - Ssumday, AnDa, Ryu, Rikara, Aphromoo
iG - Duke, Ning, Rookie, JackeyLove, Baolan
GRX - PK, baybay, Candy, Stitch, Koala